Building Infrastructure Leading to Diversity
Title of Research Project: Biofilm formation Research Description: Candida albicans is a naturally occurring fungus in the gut microflora that can become deadly through the formation of biofilms on medical implants in immunosuppressed patients. Biofilms form in four steps, adherence, where yeast cells adhere to a medical implant or device, initiation, where the yeast cells Read More …
Title of Research Project: Role of Tau myopathies in neurodegeneration Research Description: The ubiquitin proteasomal system (UPS) provides both a precise and a general means for the cell to dispose of biologically non-useful proteins, including mutant, misfolded, damaged, terminally modified or over-accumulated proteins. The ability of UPS to cause rapid substrate-specific proteolysis also allows it Read More …
Title of Research Project: Understanding Ubiquitin ligases in Skin Development Research Description: The epidermis, the outermost layer of skin, serves as a critical barrier against the outside environment. A common feature among epithelial tissues is the proper maintenance and formation of cell junctional protein complexes. Desmosomes are a type of cell-cell junctional protein complex that Read More …
Title of Research Project: Radiological correlation of oral health with ear infections Research Description: We are planning to examine 3D and 2D imaging to correlate anatomical measurement ear infections and the oral health of patients in the dental clinic. All the 3D images will be superimposed and the 2D imaging will be used in the Read More …
Title of Research Project: Renal vein anatomical location in regard to Inferior Vena Cava Research Description: The location of the Inferior Vena Cava, abdominal Aorta and the renal vein can vary from one person to another. We will examine scaled pictures from the gross anatomy lab to compare locations of these important anatomical structures. Renal Read More …
Title of Research Project: Modulation of cellular communication to manage traumatic brain injury Research Description: The effects of traumatic brain injury (TBI) through e. g. stroke, neurodegenerative disease, or neurotoxin consumption are grave and can be life-changing. This project strives to develop compounds that make it possible to manage the effects of TBI. Our drug Read More …
Title of Research Project: Synthesis and testing of platinum drugs for cancer treatment Research Description: In this project, new platinum compounds are being synthesized and tested in cell-based assays that allow for observation of DNA crosslinking in cells, the isolation and characterization of the adducts and the optimization of physiological and pharmacological parameters governing cell Read More …
Title of Research Project: Environmental remediation by biosorbent materials Research Description: Biosorption is an emerging remediation process that uses biological materials to remove toxic contaminants, such as heavy toxic metals and pesticides, using physio-chemical mechanisms. The proposed project would measure uptake of heavy metals by agricultural waste products such as fruit peels. Important parameters to Read More …
Title of Research Project: Understanding the role of Yorkie in Drosophila eye development. Research Description: My lab uses Drosophila melanogaster (fruit flies) to understand how cell division and cell growth are regulated in development. These processes are conserved through evolution and are also the same processes that often disrupted in human cancer development. This particular Read More …
Title of Research Project: Health Benefits of Telling your Life Story Research Description: There is strong empirical support that telling aspects of oneÉ??s life story has positive emotional and physical health effects. Surprisingly, no research has been conducted on the effects of telling a life story. This two-part (cross-sectional and longitudinal) project will 1) assess Read More …